Page 1 of 3

1. Repaglinide (Prandin) is believed to work by
A.
B.
C.
D.
E.

2. Drugs employed in reducing elevated serum cholesterol include(s)
I. gemfibrozil (Lopid)
II. cerivastatin (Baycol)
III. pioglitazone (Aetos)
A.
B.
C.
D.
E.

3. The renal excretion of amphetamines can be diminished by alkalinization of the urine. Which of the following would tend to diminish the excretion rate of amphetamine sulfate?
I. methenamine mandelate
II. acetazolamide
III. sodium bicarbonate
A.
B.
C.
D.
E.

4. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?
A.
B.
C.
D.
E.

5. Benzoyl peroxide is commonly employed in the treatment of
A.
B.
C.
D.
E.

6. Olsalazine sodium (Dipentum) is employed in the treatment of
A.
B.
C.
D.
E.

7. After oral administration, the greatest amount of iron absorption occurs in the
A.
B.
C.
D.
E.

8. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

9. Propylthiouracil is used for the same therapeutic indication as
A.
B.
C.
D.
E.

10. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

11. Prolonged activity (8 to 10 hours) is an advantage in the use of which of the following topical decongestants?
I. phenylephrine
II. oxymetazoline
III. xylometazoline
A.
B.
C.
D.
E.

12. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

13. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

14. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

15. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

16. Which of the following agents is (are) indicated for use in the treatment of emesis?
I. dronabinol (Marinol)
II. granisetron (Kytril)
III. nalbumetone (Relafen)
A.
B.
C.
D.
E.

17. Patients who are sensitive to aspirin should avoid the use of
I. codeine
II. oxaprozin
III. ibuprofen
A.
B.
C.
D.
E.

18. Zidovudine (Retrovir) is indicated for the treatment of patients with
I. hepatitis B infection
II. herpes simplex infections
III. human immunodeficiency virus (HIV) infection
A.
B.
C.
D.
E.

19. Aspirin is believed to inhibit clotting by its action on which of the following endogenous substances?
A.
B.
C.
D.
E.

20. Endorphins are
A.
B.
C.
D.
E.

21. Which of the following hormones is released from the posterior pituitary gland?
I. growth hormone
II. follicle-stimulating hormone (FSH)
III. oxytocin
A.
B.
C.
D.
E.

22. Clonidine may best be described as a (an)
A.
B.
C.
D.
E.

23. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

24. Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development of
A.
B.
C.
D.
E.

25. Which one of the following barbiturates is likely to be the shortest acting?
A.
B.
C.
D.
E.

26. Reduced clotting ability of the blood is associated with the administration of
I. clopidogrel (Plavix)
II. abciximab (ReoPro)
III. filgrastim (Neupogen)
A.
B.
C.
D.
E.

27. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

28. The use of clozapine (Clozaril) has been associated with the development of
A.
B.
C.
D.
E.

29. Alteplase (Activase) is an example of a tissue plasminogen activator. Which of the following describes the characteristics of this drug?
I. administered orally
II. stimulates erythrocyte production
III. produced by recombinant DNA technology
A.
B.
C.
D.
E.

30. In the treatment of cardiac arrhythmias, sotalol (Betapace) is most similar in action to
A.
B.
C.
D.
E.

31. Which of the following is (are) true of sim-vastatin (Zocor)?
I. HMG-CoA reductase inhibitor
II. pregnancy category X
III. antiviral
A.
B.
C.
D.
E.

32. Patients receiving amiodarone (Cordarone) should be monitored for the development of
A.
B.
C.
D.
E.

33. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

34. Which of the following agents is (are) used for the treatment of migraine headaches?
I. rizatriptan benzoate
II. methysergide maleate
III. succinylcholine chloride
A.
B.
C.
D.
E.

35. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

36. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

37. Colestipol HCl (Colestid) can best be classified as a (an)
A.
B.
C.
D.
E.

38. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

39. Methadone (Dolophine) is a (an)
I. analgesic drug
II. controlled substance
III. narcotic antagonist
A.
B.
C.
D.
E.

40. Which one of the following beta-adrenergic blocking agents has the greatest lipid solubility?
A.
B.
C.
D.
E.

41. Prednisone is an agent that is employed in the treatment of
I. fungal infections
II. Crohn's disease
III. rheumatic disorders
A.
B.
C.
D.
E.

42. Gingival hyperplasia, hirsutism, and ataxia are adverse effects associated with the use of
A.
B.
C.
D.
E.

43. Nerves in the human body that transmit their impulses by releasing acetylcholine are known as ...... nerves.
A.
B.
C.
D.
E.

44. Which of the following agents decreases the production of hydrochloric acid in the stomach?
I. olsalazine
II. calcium carbonate
III. lansoprazole
A.
B.
C.
D.
E.

45. The primary site of action of triamterene (Dyrenium) and spironolactone (Aldactone) is the
A.
B.
C.
D.
E.

46. Which one of the following antibiotics is a third-generation cephalosporin?
A.
B.
C.
D.
E.

47. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

48. Benzodiazepines appear to act as anxiolytics by
A.
B.
C.
D.
E.

49. Which of the following is (are) true of fentanyl?
I. available as a transdermal system
II. used as a local anesthetic
III. may be used as a cough suppressant
A.
B.
C.
D.
E.

50. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

51. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

52. During ovulation, peak plasma concentration(s) of which of the following hormone(s) will be reached?
I. luteinizing hormone (LH)
II. follicle-stimulating hormone (FSH)
III. progesterone
A.
B.
C.
D.
E.

53. Which of the following drugs is (are) classified as a selective serotonin reuptake inhibitor (SSRI)?
I. citalopram (Celexa)
II. sertraline (Zoloft)
III. venlafaxine (Effexor)
A.
B.
C.
D.
E.

54. Which of the following drugs are available in a transdermal form for the prevention of motion sickness?
A.
B.
C.
D.
E.

55. An agent that would be most likely to cause drug-induced bronchospasm is
A.
B.
C.
D.
E.

56. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

57. Which one of the following antimicrobial agents would be MOST useful in the treatment of an infection caused by beta-Iactamase-producing staphylococci?
A.
B.
C.
D.
E.

58. Which of the following is (are) true of isotretinoin (Accutane)?
I. in pregnancy category X
II. indicated for the treatment of psoriasis
III. useful for treatment of alopecia
A.
B.
C.
D.
E.

59. A common adverse effect associated with the chronic use of magnesium antacids is
A.
B.
C.
D.
E.

60. Lactase enzyme is available for the treatment of
A.
B.
C.
D.
E.