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1. Tamoxifen (Nolvadex) can best be characterized as a (an)
A.
B.
C.
D.
E.

2. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

3. Which of the following agents is NOT likely to reduce blood sugar in a patient with type II diabetes mellitus?
I. glucagon
II. pioglitazone
III. repaglinide
A.
B.
C.
D.
E.

4. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

5. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

6. The pharmacological properties of which one of the following agents is similar to amphetamine?
A.
B.
C.
D.
E.

7. Metoclopramide (Reglan) is most similar in action to which of the following drugs?
A.
B.
C.
D.
E.

8. Aspirin is believed to inhibit clotting by its action on which of the following endogenous substances?
A.
B.
C.
D.
E.

9. The agent most similar in pharmacological action to miglitol (Glyset) is
A.
B.
C.
D.
E.

10. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

11. The use of clozapine (Clozaril) has been associated with the development of
A.
B.
C.
D.
E.

12. Which of the following cancer chemotherapeutic agents is (are) classified as an antimetabolite?
I. mercaptopurine (Purinethol)
II. fluorouracil (Adrucil)
III. cytarabine (Cytosar-U)
A.
B.
C.
D.
E.

13. Which of the following is (are) classified as aminopenicillins?
I. bacampicillin
II. amoxicillin
III. ampicillin
A.
B.
C.
D.
E.

14. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors?
I. fluvastatin
II. nitroprusside
III. acetazolamide
A.
B.
C.
D.
E.

15. Which of the following is (are) true of alteplase (Activase)?
A.
B.
C.
D.
E.

16. Which one of the following barbiturates is likely to be the shortest acting?
A.
B.
C.
D.
E.

17. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

18. Simvastatin (Zocor) acts by
A.
B.
C.
D.
E.

19. Repaglinide (Prandin) is believed to work by
A.
B.
C.
D.
E.

20. Which of the following is (are) dopaminergic antiparkinson agents?
I. ropinirole (Requip)
II. pergolide (Permax)
III. procyclidine (Kemadrin)
A.
B.
C.
D.
E.

21. Which of the following can be classified as an osmotic laxative?
A.
B.
C.
D.
E.

22. Beta carotene is considered to be a precursor for
A.
B.
C.
D.
E.

23. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

24. Vidarabine (Vira-A) is an antiviral agent indicated for the treatment of
A.
B.
C.
D.
E.

25. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

26. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

27. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

28. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

29. Agent(s) indicated for the treatment of depression include(s)
I. bupropion (Wellbutrin)
II. venlafaxine (Effexor)
III. citalopram (Celexa)
A.
B.
C.
D.
E.

30. Clonidine may best be described as a (an)
A.
B.
C.
D.
E.

31. Which one of the following drugs is employed in treating acute attacks of gout?
A.
B.
C.
D.
E.

32. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

33. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

34. Which of the following beta-adrenergic blocking agents is beta1-selective?
I. betaxolol (Betoptic)
II. metipranolol HCl (OptiPranolol)
III. timolol (Timoptic)
A.
B.
C.
D.
E.

35. Which of the following drugs may interfere with ethanol metabolism?
I. metronidazole (Flagyl)
II. chlorpropamide (Diabinese)
III. disulfiram (Antabuse)
A.
B.
C.
D.
E.

36. Which of the following is (are) true of sal-meterol (Serevent)?
I. for the treatment of acute asthma attacks
II. available in an aerosol and inhalation powder form
III. beta 2 agonist
A.
B.
C.
D.
E.

37. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

38. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect by
A.
B.
C.
D.
E.

39. Which one of the following antihistamines would be LEAST likely to cause sedation?
A.
B.
C.
D.
E.

40. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

41. Which of the following is (are) true of sim-vastatin (Zocor)?
I. HMG-CoA reductase inhibitor
II. pregnancy category X
III. antiviral
A.
B.
C.
D.
E.

42. Which one of the following agents is most similar in action to cloxacillin?
A.
B.
C.
D.
E.

43. Which of the following is (are) true of finasteride (Proscar, Propecia)?
I. pregnancy category X
II. employed in the treatment of BPH
III. used in alopecia treatment
A.
B.
C.
D.
E.

44. Alteplase (Activase) is employed clinically as a (an)
A.
B.
C.
D.
E.

45. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

46. Auranofin (Ridaura) is employed in the treatment of
A.
B.
C.
D.
E.

47. Pamidronate sodium (Aredia) is indicated for the treatment of
A.
B.
C.
D.
E.

48. The dose of liothyronine sodium that is approximately equivalent to 100 ).!g of levothyroxine sodium (Synthroid) USP is
A.
B.
C.
D.
E.

49. Benzodiazepines appear to act as anxiolytics by
A.
B.
C.
D.
E.

50. Which of the following is (are) true of pentamidine isethionate (Pentam, NebuPent, Pentacarinat)?
I. may be administered by inhalation
II. may be administered parenterally
III. used to treat RSV infections
A.
B.
C.
D.
E.

51. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

52. After oral administration, the greatest amount of iron absorption occurs in the
A.
B.
C.
D.
E.

53. Which of the following statements is (are) true of "crack"?
I. It is a free-base form of cocaine.
II. Its use results in eNS depression.
III. It is generally injected intravenously.
A.
B.
C.
D.
E.

54. Minoxidil is an antihypertensive agent that works by
A.
B.
C.
D.
E.

55. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

56. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

57. Alteplase (Activase) is an example of a tissue plasminogen activator. Which of the following describes the characteristics of this drug?
I. administered orally
II. stimulates erythrocyte production
III. produced by recombinant DNA technology
A.
B.
C.
D.
E.

58. Lactase enzyme is available for the treatment of
A.
B.
C.
D.
E.

59. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidol
A.
B.
C.
D.
E.

60. Which of the following beta-adrenergic blocking agents also exhibit alpha1-adrenergic blocking action?
I. timolol (Blocadren)
II. sotalol (Betapace)
III. labetalol (Normodyne, Trandate)
A.
B.
C.
D.
E.