Pharmacology Questions Bank 1.0<<123456789101112131415161718192021222324252627282930313233343536373839404142434445464748495051525354555657585960616263646566676869707172737475767778798081828384858687888990919293949596979899100101102103104105106107108109110111112113114115116117118119120121122123124125126127128129130131132133134135136137138139140141142143144145146147148149150151152153154155156157158159160161162163164165166167168169170171172173174175176177178179180>>Read moreGeneral Pediatric-related - MCQs 1-10Page 1 of 3 Loading...1. Benzodiazepines appear to act as anxiolytics byA. altering the sodium ion influx into the CNSB. potentiating the effects of GABAC. altering the calcium ion influx into the CNSD. interfering with the amine pumpE. inhibiting the action of monoamine oxidase Loading...2. Acyclovir (Zovirax) is indicated for the treatment ofA. multiple sclerosisB. psoriasisC. HIV infectionD. shinglesE. mononucleosisRead moreThe following represents an essential element to an effective quality council? Loading...3. During ovulation, peak plasma concentration(s) of which of the following hormone(s) will be reached? I. luteinizing hormone (LH) II. follicle-stimulating hormone (FSH) III. progesteroneA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...4. Which of the products listed below are vaccines? I. Sandimmune II. Prograf III. LYMErixA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...5. Effects expected as a result of inhaling the smoke of cannabis (marijuana) include I. decreased pulse rate II. perceptual changes III. vascular congestion of the eyeA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...6. Which one of the following antihistamines would be LEAST likely to cause sedation?A. azatadine (Optimine)B. dimenhydrinate (Dramamine)C. clemastine (Tavist)D. loratidine (Claritin)E. tripelennamine (PBZ) Loading...7. Which of the following is (are) classified as a monoamine oxidase inhibitor? I. isocarboxazid (Marplan) II. phenylzine (Nardi!) III. tranylcypromine (Parnate)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III only Loading...8. Which one of the following drugs is employed in treating acute attacks of gout?A. colchicineB. ergonavine maleate (Ergotrate)C. buspirone (BuSpar)D. alendronate (Fosamax)E. allopurinol (Zyloprim) Loading...9. Which of the following antianxiety agents causes the least sedation?A. diazepam (Valium)B. buspirone (BuSpar)C. chlordiazepoxide (Librium)D. meprobamate (Miltown, Equanil)E. oxazepam (Serax) Loading...10. Dalteparin sodium (Fragmin) acts in the body toA. regulate menstrual activityB. prevent blood dot formationC. inhibit thyroid functionD. inhibit viral replicationE. reduce the secretion of acid in the stomach Loading...11. Amrinone (Inocor) is a drug that producesA. bronchodilationB. antidepressant actionC. positive inotropismD. narcotic antagonismE. enhanced protein utilization Loading...12. Which of the following is true of finasteride (Propecia, Proscar)? I. useful in treating BPH II. used to treat some types of alopecia III. a corticosteroidA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III only Loading...13. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline isA. inactivation of hepatic enzymesB. the corrosive action of the poison on the stomach liningC. the paralysis of peristaltic motion of the GI tractD. dissolution of the mucus coat of the esophagusE. the aspiration of the poison into the respiratory tract Loading...14. Which of the following is a COMT inhibitor?A. selegilineB. carbidopaC. disulfiramD. tolcaponeE. pramipexole Loading...15. Hypoparathyroidism is a disorder that would most logically be treated withA. entacaponeB. prednisoneC. liothyronineD. phytonadioneE. dihydrotachysterol Loading...16. Which of the following agents is (are) indicated for the treatment of chronic inflammatory bowel disease?A. misoprostol (Cytotec)B. ritodrine (Yutopar)C. mesalamine (Asacol)D. metoclopramide (Reglan)E. omeprazole (Prilosec) Loading...17. A uricosuric drug is one thatA. decreases urine flowB. promotes excretion of uric acid in the urineC. blocks excretion of uric acid in the urineD. aids in the tubular reabsorption of uric acidE. increases urine flow Loading...18. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?A. mioticB. decreases the production of aqueous humorC. interferes with the enzyme carbonic an hydraseD. prostaglandin agonistE. mydriatic Loading...19. Which one of the following antimicrobial agents would be MOST useful in the treatment of an infection caused by beta-Iactamase-producing staphylococci?A. dicloxacillinB. cephapirinC. cephalexinD. amoxicillinE. bacampicillin Loading...20. Lactulose is used to treat I. constipation II. portal-systemic encephalopathy III. renal tubular necrosisA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...21. Liotrix is a thyroid preparation that contains I. desiccated thyroid II. levothyroxine sodium III. liothyronine sodiumA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...22. Sulfones such as dapsone are employed commonly in the treatment ofA. urinary tract infectionsB. psoriasisC. urinary incontinenceD. atrial flutterE. leprosy Loading...23. Which of the following is true of pilocarpine (Isopto Carpine, Pilostat)? I. similar pharmacologic action to dorzolamide (Trusopt) II. direct-acting mydriatic III. ingredient in Ocusert ocular therapeutic systemA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...24. Which of the following is (are) true of fentanyl? I. available as a transdermal system II. used as a local anesthetic III. may be used as a cough suppressantA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...25. Finasteride (Proscar, Propecia) can best be described as a (an)A. androgen inhibitorB. estrogen inhibitorC. androgenD. estrogenE. progestin analog Loading...26. Which of the following is (are) true of iso-tretinoin (Accutane)?A. may be used safely in pregnant patients after the first trimesterB. a derivative of vitamin DC. is applied topically to severe acne lesionsD. contraindicated in patients with diabetesE. commonly causes cheilitis Loading...27. Stavudine (Zerit) is an antiviral agent employed in the treatment ofA. HIV infectionB. influenza A virusC. lupus erythematosusD. herpes zosterE. Mycobacterium avium complex Loading...28. Which of the following beta-adrenergic blocking agents also exhibit alpha1-adrenergic blocking action? I. timolol (Blocadren) II. sotalol (Betapace) III. labetalol (Normodyne, Trandate)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...29. Which of the following is (are) considered to be prokinetic agents? I. lansoprazole II. diphenoxylate III. metoclopramideA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...30. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidolA. is not an antipsychotic agentB. does not produce extrapyramidal effectsC. cannot be administered parenterallyD. does not cause sedationE. is not a phenothiazine Loading...31. Patients receiving amiodarone (Cordarone) should be monitored for the development ofA. pulmonary toxicityB. pseudomembranous enterocolitisC. ptosisD. stasis dermatitisE. tinnitus Loading...32. Sumatriptan (Imitrex) is most commonly employed in the treatment ofA. partial seizuresB. arthritic painC. arrhythmiasD. psoriasisE. migraine headaches Loading...33. Endorphins areA. endogenous neurotransmittersB. a new class of topical anti-inflammatory agentsC. neuromuscular blocking agentsD. biogenic amines believed to cause schizophreniaE. endogenous opioid peptides Loading...34. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of 1. doxazosin (Cardura) II. enalapril (Vasotec) III. sotalol (Betapace)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III only Loading...35. Which of the following is (are) true of pentamidine isethionate (Pentam, NebuPent, Pentacarinat)? I. may be administered by inhalation II. may be administered parenterally III. used to treat RSV infectionsA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...36. Prednisone is an agent that is employed in the treatment of I. fungal infections II. Crohn's disease III. rheumatic disordersA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...37. Which of the following agents decreases the production of hydrochloric acid in the stomach? I. olsalazine II. calcium carbonate III. lansoprazoleA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...38. Which of the following statements is (are) true of potassium? I. It is a divalent cation. II. It facilitates the utilization of glucose by cells. III. It is the principal intracellular ion.A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...39. Which of the following drugs is (are) classified as a selective serotonin reuptake inhibitor (SSRI)? I. citalopram (Celexa) II. sertraline (Zoloft) III. venlafaxine (Effexor)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...40. Gingival hyperplasia, hirsutism, and ataxia are adverse effects associated with the use ofA. minoxidil (Loniten)B. phenytoin (Dilantin)C. ginseng rootD. chlorpromazine (Thorazine)E. ciprofloxacin (Cipro) Loading...41. Thiazide diuretics decrease the excretion ofA. chlorideB. uric acidC. sodiumD. potassiumE. creatinine Loading...42. In the treatment of cardiac arrhythmias, sotalol (Betapace) is most similar in action toA. tocainideB. verapamilC. amiodaroneD. digoxinE. flecainide Loading...43. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?A. 480,000B. 300,000C. 1600D. 270,000E. 960,000 Loading...44. The primary site of action of triamterene (Dyrenium) and spironolactone (Aldactone) is theA. glomerulusB. descending loop of HenleC. ascending loop of HenleD. proximal tubuleE. distal tubule Loading...45. After oral administration, the greatest amount of iron absorption occurs in theA. ascending colonB. stomachC. duodenumD. transverse colonE. sigmoid colon Loading...46. Which of the following agents is (are) classified as a leukotriene receptor antagonist? I. ipratropium bromide II. zileuton III. montelukast sodiumA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III only Loading...47. Which of the following drugs is (are) sulfonamides?A. mafenideB. tacrolimusC. tramadolD. busulfanE. milrinone Loading...48. Which one of the following barbiturates is likely to be the shortest acting?A. amobarbital sodiumB. methohexital sodiumC. pentobarbital sodiumD. mephobarbitalE. phenobarbital Loading...49. Metoclopramide (Reglan) is most similar in action to which of the following drugs?A. bisacodylB. orlistatC. loperamideD. cisaprideE. dicyclomine Loading...50. Which of the following drugs is (are) H1-histamine receptor antagonists? I. diphenhydramine II. hydroxyzine III. famotidineA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...51. Phosphate binding is likely to occur when which of the following antacids are administered? I. aluminum hydroxide II. sodium bicarbonate III. calcium carbonateA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...52. A drug indicated for the treatment of both diarrhea and constipation isA. bisacodyl (Dulcolax)B. lactulose (Cephulac)C. polycarbophil (Mitrolan)D. senna (Senokot)E. magnesium sulfate Loading...53. Which of the following agents have cortical stimulant action? I. buspirone II. pemoline III. methamphetamineA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...54. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPTA. greater anti-inflammatory actionB. less gastric irritationC. no occult blood lossD. no appreciable effect on uric acid excretionE. no alteration of bleeding time Loading...55. Which of the following is (are) classified as a broad-spectrum antifungal agent? I. fluorouracil II. mebendazole III. miconazoleA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...56. Which of the following drugs is (are) classified as protease inhibitors? I. cidofovir II. acyclovir III. nelfinavirA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...57. Trifluridine is useful in the treatment of epithelial keratitis caused byA. herpes simplexB. Pseudomonas aeruginosaC. Staphylococcus aureusD. Clostridium difficileE. Escherichia coli Loading...58. Ramipril HCl (Altace) can best be classified as a (an)A. beta-adrenergic blocking agentB. vasodilatorC. calcium channel blockerD. angiotensin-converting enzyme inhibitorE. alpha-adrenergic blocking agent Loading...59. Which of the following agents is (are) indicated for use in the treatment of emesis? I. dronabinol (Marinol) II. granisetron (Kytril) III. nalbumetone (Relafen)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...60. Which of the following is (are) true of sim-vastatin (Zocor)? I. HMG-CoA reductase inhibitor II. pregnancy category X III. antiviralA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and IIIPage 2 of 3 Loading...61. Which of the following is (are) true of ticlopidine HCl (Ticlid)? I. inhibits platelet aggregation II. dissolves blood clots III. only administered parenterallyA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...62. Which of the following is (are) employed as an antifungal agent? I. cycloserine II. mafenide III. terbinafineA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...63. Which of the following agents are classified as macrolides? I. amikacin II. polymyxin B III. azithromycinA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...64. Diflunisal (Dolobid) is most likely to be prescribed for the treatment ofA. Wilson's diseaseB. rheumatoid arthritisC. cysteinuriaD. psoriasisE. Hansen's disease Loading...65. Which of the following is (are) classified as aminopenicillins? I. bacampicillin II. amoxicillin III. ampicillinA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...66. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?A. ritodrine (Yutopar)B. amoxapine (Asendin)C. desmopressin acetate (DDAVP)D. metolazone (Zaroxolyn)E. mannitol (Osmitrol) Loading...67. Aspirin is believed to inhibit clotting by its action on which of the following endogenous substances?A. endorphin AB. xanthine oxidaseC. fibrinogenD. cyclooxygenaseE. dopa decarboxylase Loading...68. Which of the following hormones is released from the posterior pituitary gland? I. growth hormone II. follicle-stimulating hormone (FSH) III. oxytocinA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...69. Which of the following is (are) true of milrinone lactate (Primacor)? I. may be administered orally or parenterally II. produces a positive inotropic action III. produces vasodilationA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...70. Propylthiouracil is used for the same therapeutic indication asA. methoxsalenB. danazolC. azathioprineD. omeprazoleE. methimazole Loading...71. Which of the following drugs may be used in the treatment of diabetes insipidus?A. chlorpropamide (Diabinese)B. lypressin (Diapid)C. insulinD. glyburide (Micronase)E. glucagon Loading...72. Tamoxifen (Nolvadex) can best be characterized as a (an)A. gonadotropin-releasing hormone analogB. estrogenC. antiestrogenD. progestinE. androgen Loading...73. Benzoyl peroxide is commonly employed in the treatment ofA. psoriasisB. pinwormsC. seborrheic dermatitisD. trichomonal infectionsE. acne Loading...74. The thiazide derivative diazoxide (Hyperstat)A. is a more potent diuretic than hydrochlorothiazideB. is not a diureticC. produces about the same diuretic response as an equal dose of hydrochlorothiazideD. is used in the treatment of shockE. must be used with a potassium supplement Loading...75. Simvastatin (Zocor) acts byA. inhibiting xanthine oxidaseB. inhibiting HMG-CoA reductaseC. inhibiting acetylcholinesteraseD. acting as a bile sequestrantE. interfering with fat absorption from the GI Loading...76. The dose of liothyronine sodium that is approximately equivalent to 100 ).!g of levothyroxine sodium (Synthroid) USP isA. 120 )McgB. 0.4 )McgC. 250 )McgD. 25 )McgE. 100 )Mcg Loading...77. Vidarabine (Vira-A) is an antiviral agent indicated for the treatment ofA. rubellaB. AIDSC. influenzaD. herpes simplex encephalitisE. pneumocystis carinii pneumonia (PCP) Loading...78. Which of the following agents is (are) used as anorexiants? I. sibutramine (Meridia) II. mazindol (Sanorex, Mazanor) III. benzphetamine (Didrex)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...79. Which one of the following agents is most similar in action to cloxacillin?A. amoxicillin (Amoxil)B. bacampicillin (Spectrobid)C. penicillin V potassium (Pen Vee K)D. nafcillin (Unipen, Nallpen)E. ticarcillin (Ticar) Loading...80. Which of the following is (are) dopaminergic antiparkinson agents? I. ropinirole (Requip) II. pergolide (Permax) III. procyclidine (Kemadrin)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...81. Which of the following antiarrhythmic agents is (are) associated with an adverse effect known as cinchonism?A. acebutololB. moricizineC. quinidineD. lidocaineE. disopyramide Loading...82. The primary function of simethicone in antacid products is to act as a (an)A. suspending agentB. adsorbentC. bufferD. antiflatulentE. flavoring agent Loading...83. Which of the following is (are) true of alteplase (Activase)?A. derived from bovine tissueB. administered intramuscularlyC. derived from porcine tissueD. an anticoagulantE. a thrombolytic agent Loading...84. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors? I. fluvastatin II. nitroprusside III. acetazolamideA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III only Loading...85. Isotretinoin (Accutane) is a drug employed in the treatment of severe recalcitrant cystic acne. Which one of the following is NOT an adverse effect associated with its use?A. hypertriglyceridemiaB. hyperglycemiaC. pseudotumor cerebriD. conjunctivitisE. fetal abnormalities Loading...86. The pharmacological properties of which one of the following agents is similar to amphetamine?A. methdilazineB. lithium carbonateC. methylphenidateD. haloperidolE. methoxsalen Loading...87. Which of the following is true of permethrin (Nix, Elimite)? I. It is only used topically. II. It is used to treat topical fungal infections. III. It is used to enhance permeation of drugs through the skin.A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...88. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action ofA. monoamine oxidaseB. p-aminobenzoic acidC. pyrimidineD. beta lactamaseE. DNA polymerase Loading...89. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?A. It should only be used in the treatment of an acute asthmatic attack.B. It should not be used in a patient who is currently using a theophylline product.C. Beclomethasone is not systemically absorbed by this route.D. If used in conjunction with a bronchodilator administered by inhalation, the bronchodilator should be used first.E. The aerosol form is also useful in the treatment of status asthmaticus. Loading...90. Patients who are sensitive to aspirin should avoid the use of I. codeine II. oxaprozin III. ibuprofenA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...91. Which of the following statements is (are) true of metronidazole (Flagyl)? I. It is indicated for the treatment of migraine headaches. II. It is used to treat superficial fungal infections. III. It has antiprotozoal activity.A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...92. Which of the following agents is NOT likely to reduce blood sugar in a patient with type II diabetes mellitus? I. glucagon II. pioglitazone III. repaglinideA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...93. Which of the following statements is (are) true of "crack"? I. It is a free-base form of cocaine. II. Its use results in eNS depression. III. It is generally injected intravenously.A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...94. Carbon monoxide exerts its toxic effects primarilybyA. inhibiting the gag reflexB. decreasing the oxygen-carrying capacity of the bloodC. reacting with amino acids in the body to form ammoniaD. reacting with body enzymes to produce respiratory acidosisE. paralyzing the muscles of the diaphragm Loading...95. Colestipol HCl (Colestid) can best be classified as a (an)A. HMG-CoA reductase inhibitorB. vasopressorC. potassium-sparing diureticD. ACE inhibitorE. bile acid sequestrant Loading...96. Which of the following agents is (are) classified as antiseptics or germicides? I. chlorhexidine gluconate (Hibiclens) II. glutaraldehyde (Cidex) III. benzalkonium chloride (Zephiran)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...97. Cromolyn sodium (Intal, Nasalcrom, Opticrom) is a drug that isA. effective in acute asthmatic attacksB. a synthetic corticosteroidC. a histamine antagonistD. a mast cell stabilizerE. a leukotriene inhibitor Loading...98. Carbidopa can best be classified as a drug thatA. reverses symptoms of Parkinson's diseaseB. exerts an anticholinergic actionC. is a dopaminergic agentD. is a neuromuscular blocking agentE. is a dopa-decarboxylase inhibitor Loading...99. Minoxidil is an antihypertensive agent that works byA. potentiating GABA activityB. directly dilating peripheral blood vesselsC. blocking alpha-adrenergic receptorsD. inhibiting COMTE. blocking beta-adrenergic receptors Loading...100. Danazol (Danocrine) can best be classified as a (an)A. anti-inflammatory corticosteroidB. estrogenC. progestinD. neuromuscular blocking agentE. androgen Loading...101. Repaglinide (Prandin) is believed to work byA. decreasing the absorption of carbohydratesB. decreasing hepatic gluconeogenesisC. stimulating the release of insulin from the pancreasD. increasing hepatic gluconeogenesisE. reducing glucagon secretion from the pancreas Loading...102. Alteplase (Activase) is an example of a tissue plasminogen activator. Which of the following describes the characteristics of this drug? I. administered orally II. stimulates erythrocyte production III. produced by recombinant DNA technologyA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...103. Which of the following are employed clinically as intranasal steroids? I. budesonide (Rhinocort) II. fluticasone propionate (Flonase) III. nedocromil (Tilade)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...104. Which of the following cancer chemotherapeutic agents is (are) classified as an antimetabolite? I. mercaptopurine (Purinethol) II. fluorouracil (Adrucil) III. cytarabine (Cytosar-U)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...105. An agent that would be most likely to cause drug-induced bronchospasm isA. cromolynB. benazeprilC. isoproterenolD. fluvastatinE. sotalol Loading...106. Which of the following is an active metabolite of primidone (Mysoline)? I. acetylcholine II. phenylethylmalonamide III. phenobarbitalA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...107. A disadvantage in the use of cimetidine (Tagamet) is its ability to causeA. cheilosisB. aplastic anemiaC. inhibition of hepatic enzyme activityD. gastric hyperparesisE. decreased prolactin secretion Loading...108. Reflex tachycardia is an adverse effect most likely to be associated with the use of which of the following drugs?A. minoxidil (Loniten)B. losartan (Cozaar)C. moexipril (Univasc)D. nadolol (Corgard)E. clonidine (Catapres) Loading...109. Which of the following is true of naratriptan (Amerge)? I. It is a 5-HT1-receptor antagonist. II. It may be administered orally or by inhalation. III. It must be used regularly to prevent migraine headaches.A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...110. Which of the following bronchodilators act by inhibiting phosphodiesterase? I. dyphylline (Lufyllin) II. salmeterol (Serevent) III. nedocromil sodium (Tilade)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...111. Most antipsychotic drugs can be said to have which of the following actions?A. cholinergicB. dopaminergicC. COMT inhibitionD. dopamine inhibitionE. alpha1-adrenergic agonist Loading...112. Which of the following can be classified as an osmotic laxative?A. milk of magnesiaB. sennaC. cascara sagradaD. docusate sodiumE. castor oil Loading...113. Which of the following statements is (are) true of regular insulin? I. It is a suspension. II. It may be administered either SC or IV. III. It is longer acting than lispro insulin.A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...114. Latanoprost (Xalatan) can best be described as a (an)A. cholinesterase inhibitorB. osmotic diureticC. beta-adrenergic blocking agentD. prodrugE. prostaglandin agonist Loading...115. Which one of the following is an effect of atropine on the human body?A. decreased heart rateB. decreased sweatingC. produces miosisD. increased gastrointestinal motilityE. stimulates gastric secretion Loading...116. Which of the following drugs may interfere with ethanol metabolism? I. metronidazole (Flagyl) II. chlorpropamide (Diabinese) III. disulfiram (Antabuse)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III only Loading...117. Which of the following agents is (are) used for the treatment of migraine headaches? I. rizatriptan benzoate II. methysergide maleate III. succinylcholine chlorideA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...118. Which of the following beta-adrenergic blocking agents is beta1-selective? I. betaxolol (Betoptic) II. metipranolol HCl (OptiPranolol) III. timolol (Timoptic)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...119. Nerves in the human body that transmit their impulses by releasing acetylcholine are known as ...... nerves.A. adrenergicB. cholinergicC. sympatheticD. anticholinergicE. neurogenic Loading...120. Which of the following calcium channel blockers may be employed parenterally in the treatment of cardiac arrhythmias? I. verapamil (Isoptin, Calan) II. isradipine (DynaCirc) III. amlodipine (Norvasc)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and IIIPage 3 of 3 Loading...121. An advantage of salmeterol (Serevent) over isoproterenol (Isuprel) in the treatment of bronchial asthma is that salmeterolA. is more selective for beta2-adrenergic receptorsB. has more beta-agonist activity than iso-proterenolC. has alpha-adrenergic activityD. causes less cardiac stimulationE. has a more rapid onset of action Loading...122. Didofenac sodium (Voltaren) is most similar in action toA. buspirone (BuSpar)B. oxaprozin (Daypro)C. chlorzoxazone (Paraflex)D. dicydomine (Bentyl)E. mecamylamine (Inversine) Loading...123. Which of the following agents is (are) an anabolic steroid? I. oxandrolone II. stanozolol III. fluorometholoneA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...124. The renal excretion of amphetamines can be diminished by alkalinization of the urine. Which of the following would tend to diminish the excretion rate of amphetamine sulfate? I. methenamine mandelate II. acetazolamide III. sodium bicarbonateA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III only Loading...125. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption ofA. medium chain triglyceridesB. folic acidC. ironD. cyanocobalaminE. tocopherols Loading...126. Olsalazine sodium (Dipentum) is employed in the treatment ofA. diabetes mellitusB. duodenal ulcersC. urinary tract infectionsD. ulcerative colitisE. diabetes insipidus Loading...127. Iron is required by the body to maintain normalA. leukocyte developmentB. ascorbic acid absorptionC. bone growthD. immune functionE. oxygen transport Loading...128. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?A. hydrocortisone (Corte£)B. prednisone (Meticorten)C. triamcinolone (Aristocort)D. betamethasone (Celestone)E. cortisone (Cortone) Loading...129. Nicardipine (Cardene) is indicated for the treatment of I. angina pectoris II. hypertension III. ventricular tachycardiaA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...130. A common adverse effect associated with the chronic use of magnesium antacids isA. nausea and vomitingB. gastrointestinal bleedingC. flatulenceD. diarrheaE. constipation Loading...131. Which of the following is (are) true of isotretinoin (Accutane)? I. in pregnancy category X II. indicated for the treatment of psoriasis III. useful for treatment of alopeciaA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...132. Morphine can be expected to produce which of the following pharmacological effects? I. dilation of the pupils II. respiratory depression III. constipationA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...133. The agent most similar in pharmacological action to miglitol (Glyset) isA. glipizideB. lispro insulinC. pioglitazoneD. repaglinideE. acarbose Loading...134. Which of the following is (are) true of sal-meterol (Serevent)? I. for the treatment of acute asthma attacks II. available in an aerosol and inhalation powder form III. beta 2 agonistA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...135. Which one of the following antibiotics is a third-generation cephalosporin?A. cefoxitin (Mefoxin)B. cefonicid (Monocid)C. cephalexin (Keflex)D. cefixime (Suprax)E. cefador (Cedor) Loading...136. Which of the following is a gold compound? I. aurothioglucose (Solganal) II. goserelin acetate (Zoladex) III. ergonovineA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...137. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused byA. anticholinergic agentsB. heavy metalsC. benzodiazepinesD. iron-containing productsE. alkylating agents Loading...138. Cyclophosphamide (Cytoxan) is an example of a (an)A. antibioticB. estrogen antagonistC. antimetaboliteD. alkylating agentE. prostaglandin inhibitor Loading...139. Which one of the following is NOT a progestin?A. norethynodrelB. norethindroneC. mestranolD. levonorgestrelE. ethynodiol diacetate Loading...140. Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development ofA. hepatotoxicityB. toleranceC. aplastic anemiaD. nephrotoxicityE. pseudomembranous enterocolitis Loading...141. Alteplase (Activase) is employed clinically as a (an)A. xanthine oxidase inhibitorB. proteolytic enzymeC. monoamine oxidase inhibitorD. ulcer adherent complexE. tissue plasminogen activator Loading...142. Auranofin (Ridaura) is employed in the treatment ofA. rheumatoid arthritisB. multiple sclerosisC. ulcerative colitisD. recalcitrant cystic acneE. ear infections Loading...143. Beta carotene is considered to be a precursor forA. betaseronB. beta interferonC. tocopherolD. vitamin AE. carteolol Loading...144. Lactase enzyme is available for the treatment ofA. lactose intoleranceB. galactokinase deficiencyC. cystic fibrosisD. phenylketonuriaE. Crohn's disease Loading...145. A drug that decreases the formation of uric acid isA. miglitolB. allopurinolC. probenecidD. ketamineE. propylthiouracil Loading...146. Which of the following antimicrobial products is (are) prodrugs? I. cefpodoxime proxetil II. dirithromycin III. clindamycinA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...147. Prolonged activity (8 to 10 hours) is an advantage in the use of which of the following topical decongestants? I. phenylephrine II. oxymetazoline III. xylometazolineA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...148. Which of the following statements is (are) true of fentanyl? I. It is a narcotic agonist analgesic. II. It is available as a transmucosal system. III. It is available as a transdermal system.A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...149. The anti-inflammatory effect of NSAIDs is due to their ability to 1. inhibit prostaglandin synthesis II. inhibit the stimulation of the chemoreceptor trigger zone (CTZ) III. reset the hypothalamic "setpoint"A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...150. Which of the following morphine derivatives is most likely to cause dependence?A. diacetylmorphineB. ethylmorphineC. methylmorphineD. hydrocodoneE. oxycodone Loading...151. Which one of the following statements best describes the mechanism of action of ranitidine (Zantac)?A. It interferes with the synthesis of histamine in the body.B. It forms an inactive complex with histamine.C. It stimulates the metabolism of endogenous histamine.D. It blocks the receptor sites on which histamine acts.E. It directly inhibits the action of mucin in the stomach. Loading...152. Which of the following drugs are available in a transdermal form for the prevention of motion sickness?A. metoclopramideB. ondansetronC. granisetronD. clonidineE. scopolamine Loading...153. Which of the following is (are) true of dobut amine (Dobutrex)? I. antidepressant II. only administered parenterally III. beta! agonistA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...154. Which one of the following is an example of a pure narcotic antagonist?A. butorphanol (Stadol)B. buprenorphine (Buprenex)C. nalbuphine HCl (Nubain)D. naltrexone (ReVia)E. sufentanil (Sufenta) Loading...155. Pamidronate sodium (Aredia) is indicated for the treatment ofA. Crohn's diseaseB. Meniere's syndromeC. Paget's diseaseD. Hansen's diseaseE. Parkinson's disease Loading...156. Agent(s) indicated for the treatment of depression include(s) I. bupropion (Wellbutrin) II. venlafaxine (Effexor) III. citalopram (Celexa)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...157. Methadone (Dolophine) is a (an) I. analgesic drug II. controlled substance III. narcotic antagonistA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...158. Lactulose (Cephulac, Chronulac) I. is a laxative II. decreases blood ammonia levels III. is an artificial sweetenerA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...159. Timentin is a product that contains ticarcillin disodium and clavulanate potassium. Clavulanate potassiumA. inhibits beta-Iactamase enzymesB. prevents the urinary excretion of ticarcillin disodiumC. prevents first-pass metabolism of ticarcillin disodiumD. is a bufferE. is an antifungal agent Loading...160. Which one of the following agents can be administered with ampicillin and other penicillins to achieve higher blood levels of the penicillin?A. clavulanic acidB. penicillamine (Cuprimine)C. probenecid (Benemid)D. colchicineE. sulbactam Loading...161. Which of the following statements is (are) TRUE of buprenorphine (Buprenex)? I. It is a narcotic agonist-antagonist drug. II. It is only administered parenterally. III. It is a phenothiazine derivative.A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...162. Zidovudine (Retrovir) is indicated for the treatment of patients with I. hepatitis B infection II. herpes simplex infections III. human immunodeficiency virus (HIV) infectionA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...163. Torsemide (Demadex) is most similar in action toA. bumetanide (Bumex)B. risperidone (Risperdal)C. spironolactone (Aldactone)D. chlorthalidone (Hygroton)E. acetazolamide (Diamox) Loading...164. As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents?A. amiodaroneB. propranololC. digoxinD. verapamilE. mexiletine Loading...165. Reduced clotting ability of the blood is associated with the administration of I. clopidogrel (Plavix) II. abciximab (ReoPro) III. filgrastim (Neupogen)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...166. Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an)A. immunosuppressant effectB. antiviral effectC. antiemetic effectD. cytotoxic effectE. anabolic effect Loading...167. The sulfonylureas (eg, Diabinese, Glucotrol) are believed to exert their hypoglycemic effect byA. stimulating the release of insulin from the pancreasB. inhibiting the breakdown of endogenous insulinC. decreasing the absorption of dietary glucoseD. decreasing the sensitivity of insulin receptorsE. decreasing the desire for sugar consumption Loading...168. Fluvastatin (Lescol) is contraindicated for use in patients who areA. pregnantB. hypersensitive to sulfa drugsC. chronic asthmaticsD. more than 25% over ideal body weightE. diabetic Loading...169. Which of the following is (are) true of finasteride (Proscar, Propecia)? I. pregnancy category X II. employed in the treatment of BPH III. used in alopecia treatmentA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...170. Which one of the following beta-adrenergic blocking agents has the greatest lipid solubility?A. esmolol (Brevibloc)B. atenolol (Tenormin)C. pindolol (Visken)D. acebutolol (Sectral)E. propranolol HCl (Inderal) Loading...171. Selegeline (Eldepryl) can best be described as a (an)A. MAO inhibitorB. anticholinergicC. COMT inhibitorD. anticonvulsantE. alpha! agonist Loading...172. Potassium depletion is LEAST likely to occur in a patient usingA. ethacrynic acid (Edecrin)B. triamterene (Dyrenium)C. torsemide (Demadex)D. acetazolamide (Diamox)E. chlorthalidone (Hygroton) Loading...173. Clonidine may best be described as a (an)A. alpha-adrenergic blockerB. beta-adrenergic blockerC. MAO inhibitorD. alpha-adrenergic agonistE. beta-adrenergic agonist Loading...174. The use of clozapine (Clozaril) has been associated with the development ofA. thrombocytopeniaB. hypocalcemiaC. meningitisD. agranulocytosisE. hematuria Loading...175. Didanosine (Videx) can best be described as a (an)A. antiprotozoalB. reverse transcriptase inhibitorC. protease inhibitorD. beta-lactamase inhibitorE. antifungal Loading...176. In monitoring a patient receiving warfarin for the treatment of acute myocardial infarction, it is important to maintain the INR betweenA. 2-3B. 3-5C. 5-7D. 7-9E. 9-14 Loading...177. Zafirlukast (Accolate) is a drug that can best be classified as a (an)A. leukocyte stimulantB. carbonic anhydrase inhibitorC. monoamine oxidase inhibitorD. angiotensin-converting enzyme inhibitorE. leukotriene formation inhibitor Loading...178. Drugs employed in reducing elevated serum cholesterol include(s) I. gemfibrozil (Lopid) II. cerivastatin (Baycol) III. pioglitazone (Aetos)A. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading...179. Amrinone (Inocor) is most similar in action toA. nadolol (Corgard)B. lidocaine (Xylocaine)C. valsartan (Diovan)D. disopyramide (Norpace)E. digoxin (Lanoxin) Loading...180. Which of the following agents is (are) indicated for the treatment of convulsive disorders I. clonidine II. tiagabine III. topiramateA. I onlyB. III onlyC. I and II onlyD. II and III onlyE. I, II, and III Loading... By Medical Tactics|2022-03-03T23:28:06+00:00March 3, 2022|Question Banks|0 CommentsShare This Story, Choose Your Platform!FacebookXRedditLinkedInWhatsAppTelegramTumblrPinterestVkXingEmail About the Author: Medical Tactics Related PostsUSMLE QUESTIONS BANK 2.0 USMLE QUESTIONS BANK 2.0 Easy Biology MCQs Gallery Easy Biology MCQs Easy Medical MCQs Gallery Easy Medical MCQs Medical Questions & Answers Gallery Medical Questions & Answers Leave A Comment Cancel replyComment Save my name, email, and website in this browser for the next time I comment. Hover or click the text box below or Type/Enter: med2020
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