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1. Agent(s) indicated for the treatment of depression include(s)
I. bupropion (Wellbutrin)
II. venlafaxine (Effexor)
III. citalopram (Celexa)
A.
B.
C.
D.
E.

2. Amrinone (Inocor) is a drug that produces
A.
B.
C.
D.
E.

3. Which one of the following beta-adrenergic blocking agents has the greatest lipid solubility?
A.
B.
C.
D.
E.

4. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

5. Ramipril HCl (Altace) can best be classified as a (an)
A.
B.
C.
D.
E.

6. Which of the following is (are) employed as an antifungal agent?
I. cycloserine
II. mafenide
III. terbinafine
A.
B.
C.
D.
E.

7. Which of the following is a gold compound?
I. aurothioglucose (Solganal)
II. goserelin acetate (Zoladex)
III. ergonovine
A.
B.
C.
D.
E.

8. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

9. A common adverse effect associated with the chronic use of magnesium antacids is
A.
B.
C.
D.
E.

10. In monitoring a patient receiving warfarin for the treatment of acute myocardial infarction, it is important to maintain the INR between
A.
B.
C.
D.
E.

11. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

12. Methadone (Dolophine) is a (an)
I. analgesic drug
II. controlled substance
III. narcotic antagonist
A.
B.
C.
D.
E.

13. Cyclophosphamide (Cytoxan) is an example of a (an)
A.
B.
C.
D.
E.

14. Latanoprost (Xalatan) can best be described as a (an)
A.
B.
C.
D.
E.

15. Which of the following antiarrhythmic agents is (are) associated with an adverse effect known as cinchonism?
A.
B.
C.
D.
E.

16. Which of the following agents are classified as macrolides?
I. amikacin
II. polymyxin B
III. azithromycin
A.
B.
C.
D.
E.

17. Nicardipine (Cardene) is indicated for the treatment of
I. angina pectoris
II. hypertension
III. ventricular tachycardia
A.
B.
C.
D.
E.

18. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

19. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

20. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

21. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

22. Which one of the following antihistamines would be LEAST likely to cause sedation?
A.
B.
C.
D.
E.

23. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

24. The primary site of action of triamterene (Dyrenium) and spironolactone (Aldactone) is the
A.
B.
C.
D.
E.

25. Which of the following agents have cortical stimulant action?
I. buspirone
II. pemoline
III. methamphetamine
A.
B.
C.
D.
E.

26. Carbidopa can best be classified as a drug that
A.
B.
C.
D.
E.

27. Effects expected as a result of inhaling the smoke of cannabis (marijuana) include
I. decreased pulse rate
II. perceptual changes
III. vascular congestion of the eye
A.
B.
C.
D.
E.

28. Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an)
A.
B.
C.
D.
E.

29. Lactulose is used to treat
I. constipation
II. portal-systemic encephalopathy
III. renal tubular necrosis
A.
B.
C.
D.
E.

30. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

31. Benzoyl peroxide is commonly employed in the treatment of
A.
B.
C.
D.
E.

32. Which of the following agents is (are) classified as antiseptics or germicides?
I. chlorhexidine gluconate (Hibiclens)
II. glutaraldehyde (Cidex)
III. benzalkonium chloride (Zephiran)
A.
B.
C.
D.
E.

33. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

34. A drug that decreases the formation of uric acid is
A.
B.
C.
D.
E.

35. Which of the following statements is (are) TRUE of buprenorphine (Buprenex)?
I. It is a narcotic agonist-antagonist drug.
II. It is only administered parenterally.
III. It is a phenothiazine derivative.
A.
B.
C.
D.
E.

36. Which of the following morphine derivatives is most likely to cause dependence?
A.
B.
C.
D.
E.

37. Which of the following drugs is (are) H1-histamine receptor antagonists?
I. diphenhydramine
II. hydroxyzine
III. famotidine
A.
B.
C.
D.
E.

38. Which of the following drugs are available in a transdermal form for the prevention of motion sickness?
A.
B.
C.
D.
E.

39. A disadvantage in the use of cimetidine (Tagamet) is its ability to cause
A.
B.
C.
D.
E.

40. Which of the following drugs is (are) sulfonamides?
A.
B.
C.
D.
E.

41. Which one of the following drugs is employed in treating acute attacks of gout?
A.
B.
C.
D.
E.

42. Which of the following statements is (are) true of "crack"?
I. It is a free-base form of cocaine.
II. Its use results in eNS depression.
III. It is generally injected intravenously.
A.
B.
C.
D.
E.

43. After oral administration, the greatest amount of iron absorption occurs in the
A.
B.
C.
D.
E.

44. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

45. Endorphins are
A.
B.
C.
D.
E.

46. Iron is required by the body to maintain normal
A.
B.
C.
D.
E.

47. As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents?
A.
B.
C.
D.
E.

48. Reduced clotting ability of the blood is associated with the administration of
I. clopidogrel (Plavix)
II. abciximab (ReoPro)
III. filgrastim (Neupogen)
A.
B.
C.
D.
E.

49. Alteplase (Activase) is employed clinically as a (an)
A.
B.
C.
D.
E.

50. During ovulation, peak plasma concentration(s) of which of the following hormone(s) will be reached?
I. luteinizing hormone (LH)
II. follicle-stimulating hormone (FSH)
III. progesterone
A.
B.
C.
D.
E.

51. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

52. Which of the following is (are) dopaminergic antiparkinson agents?
I. ropinirole (Requip)
II. pergolide (Permax)
III. procyclidine (Kemadrin)
A.
B.
C.
D.
E.

53. Metoclopramide (Reglan) is most similar in action to which of the following drugs?
A.
B.
C.
D.
E.

54. Which of the following is (are) classified as a monoamine oxidase inhibitor?
I. isocarboxazid (Marplan)
II. phenylzine (Nardi!)
III. tranylcypromine (Parnate)
A.
B.
C.
D.
E.

55. Which of the following is (are) true of isotretinoin (Accutane)?
I. in pregnancy category X
II. indicated for the treatment of psoriasis
III. useful for treatment of alopecia
A.
B.
C.
D.
E.

56. Which of the following agents is NOT likely to reduce blood sugar in a patient with type II diabetes mellitus?
I. glucagon
II. pioglitazone
III. repaglinide
A.
B.
C.
D.
E.

57. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

58. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.

59. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors?
I. fluvastatin
II. nitroprusside
III. acetazolamide
A.
B.
C.
D.
E.

60. Repaglinide (Prandin) is believed to work by
A.
B.
C.
D.
E.