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1. Which of the following is true of permethrin (Nix, Elimite)?
I. It is only used topically.
II. It is used to treat topical fungal infections.
III. It is used to enhance permeation of drugs through the skin.
A.
B.
C.
D.
E.

2. Endorphins are
A.
B.
C.
D.
E.

3. As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents?
A.
B.
C.
D.
E.

4. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

5. Lactase enzyme is available for the treatment of
A.
B.
C.
D.
E.

6. Morphine can be expected to produce which of the following pharmacological effects?
I. dilation of the pupils
II. respiratory depression
III. constipation
A.
B.
C.
D.
E.

7. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

8. The agent most similar in pharmacological action to miglitol (Glyset) is
A.
B.
C.
D.
E.

9. Propylthiouracil is used for the same therapeutic indication as
A.
B.
C.
D.
E.

10. Which of the following is (are) true of iso-tretinoin (Accutane)?
A.
B.
C.
D.
E.

11. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

12. Which one of the following agents can be administered with ampicillin and other penicillins to achieve higher blood levels of the penicillin?
A.
B.
C.
D.
E.

13. Which of the following is an active metabolite of primidone (Mysoline)?
I. acetylcholine
II. phenylethylmalonamide
III. phenobarbital
A.
B.
C.
D.
E.

14. Which one of the following agents is most similar in action to cloxacillin?
A.
B.
C.
D.
E.

15. Which of the following drugs is (are) H1-histamine receptor antagonists?
I. diphenhydramine
II. hydroxyzine
III. famotidine
A.
B.
C.
D.
E.

16. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

17. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

18. Which of the following is true of finasteride (Propecia, Proscar)?
I. useful in treating BPH
II. used to treat some types of alopecia
III. a corticosteroid
A.
B.
C.
D.
E.

19. Agent(s) indicated for the treatment of depression include(s)
I. bupropion (Wellbutrin)
II. venlafaxine (Effexor)
III. citalopram (Celexa)
A.
B.
C.
D.
E.

20. Which of the following agents is (are) used as anorexiants?
I. sibutramine (Meridia)
II. mazindol (Sanorex, Mazanor)
III. benzphetamine (Didrex)
A.
B.
C.
D.
E.

21. Which of the following is (are) classified as a broad-spectrum antifungal agent?
I. fluorouracil
II. mebendazole
III. miconazole
A.
B.
C.
D.
E.

22. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

23. Lactulose (Cephulac, Chronulac)
I. is a laxative
II. decreases blood ammonia levels
III. is an artificial sweetener
A.
B.
C.
D.
E.

24. Effects expected as a result of inhaling the smoke of cannabis (marijuana) include
I. decreased pulse rate
II. perceptual changes
III. vascular congestion of the eye
A.
B.
C.
D.
E.

25. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

26. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

27. Which of the following agents is (are) classified as a leukotriene receptor antagonist?
I. ipratropium bromide
II. zileuton
III. montelukast sodium
A.
B.
C.
D.
E.

28. Which of the following agents is (are) indicated for use in the treatment of emesis?
I. dronabinol (Marinol)
II. granisetron (Kytril)
III. nalbumetone (Relafen)
A.
B.
C.
D.
E.

29. Reduced clotting ability of the blood is associated with the administration of
I. clopidogrel (Plavix)
II. abciximab (ReoPro)
III. filgrastim (Neupogen)
A.
B.
C.
D.
E.

30. Prolonged activity (8 to 10 hours) is an advantage in the use of which of the following topical decongestants?
I. phenylephrine
II. oxymetazoline
III. xylometazoline
A.
B.
C.
D.
E.

31. Fluvastatin (Lescol) is contraindicated for use in patients who are
A.
B.
C.
D.
E.

32. Which of the following drugs may interfere with ethanol metabolism?
I. metronidazole (Flagyl)
II. chlorpropamide (Diabinese)
III. disulfiram (Antabuse)
A.
B.
C.
D.
E.

33. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

34. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

35. Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development of
A.
B.
C.
D.
E.

36. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

37. Drugs employed in reducing elevated serum cholesterol include(s)
I. gemfibrozil (Lopid)
II. cerivastatin (Baycol)
III. pioglitazone (Aetos)
A.
B.
C.
D.
E.

38. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

39. Zafirlukast (Accolate) is a drug that can best be classified as a (an)
A.
B.
C.
D.
E.

40. Which of the following agents is (are) classified as antiseptics or germicides?
I. chlorhexidine gluconate (Hibiclens)
II. glutaraldehyde (Cidex)
III. benzalkonium chloride (Zephiran)
A.
B.
C.
D.
E.

41. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

42. Which one of the following is NOT a progestin?
A.
B.
C.
D.
E.

43. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline is
A.
B.
C.
D.
E.

44. Colestipol HCl (Colestid) can best be classified as a (an)
A.
B.
C.
D.
E.

45. After oral administration, the greatest amount of iron absorption occurs in the
A.
B.
C.
D.
E.

46. Minoxidil is an antihypertensive agent that works by
A.
B.
C.
D.
E.

47. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

48. Which one of the following drugs is employed in treating acute attacks of gout?
A.
B.
C.
D.
E.

49. Vidarabine (Vira-A) is an antiviral agent indicated for the treatment of
A.
B.
C.
D.
E.

50. The anti-inflammatory effect of NSAIDs is due to their ability to
1. inhibit prostaglandin synthesis
II. inhibit the stimulation of the chemoreceptor trigger zone (CTZ)
III. reset the hypothalamic "setpoint"
A.
B.
C.
D.
E.

51. Which of the following is (are) true of sal-meterol (Serevent)?
I. for the treatment of acute asthma attacks
II. available in an aerosol and inhalation powder form
III. beta 2 agonist
A.
B.
C.
D.
E.

52. The thiazide derivative diazoxide (Hyperstat)
A.
B.
C.
D.
E.

53. Pamidronate sodium (Aredia) is indicated for the treatment of
A.
B.
C.
D.
E.

54. Repaglinide (Prandin) is believed to work by
A.
B.
C.
D.
E.

55. Methadone (Dolophine) is a (an)
I. analgesic drug
II. controlled substance
III. narcotic antagonist
A.
B.
C.
D.
E.

56. A uricosuric drug is one that
A.
B.
C.
D.
E.

57. Which one of the following drugs is indicated for the treatment of primary nocturnal enuresis?
A.
B.
C.
D.
E.

58. Latanoprost (Xalatan) can best be described as a (an)
A.
B.
C.
D.
E.

59. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

60. The dose of liothyronine sodium that is approximately equivalent to 100 ).!g of levothyroxine sodium (Synthroid) USP is
A.
B.
C.
D.
E.