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1. Benzodiazepines appear to act as anxiolytics by
A.
B.
C.
D.
E.

2. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

3. During ovulation, peak plasma concentration(s) of which of the following hormone(s) will be reached?
I. luteinizing hormone (LH)
II. follicle-stimulating hormone (FSH)
III. progesterone
A.
B.
C.
D.
E.

4. Which of the products listed below are vaccines?
I. Sandimmune
II. Prograf
III. LYMErix
A.
B.
C.
D.
E.

5. Effects expected as a result of inhaling the smoke of cannabis (marijuana) include
I. decreased pulse rate
II. perceptual changes
III. vascular congestion of the eye
A.
B.
C.
D.
E.

6. Which one of the following antihistamines would be LEAST likely to cause sedation?
A.
B.
C.
D.
E.

7. Which of the following is (are) classified as a monoamine oxidase inhibitor?
I. isocarboxazid (Marplan)
II. phenylzine (Nardi!)
III. tranylcypromine (Parnate)
A.
B.
C.
D.
E.

8. Which one of the following drugs is employed in treating acute attacks of gout?
A.
B.
C.
D.
E.

9. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

10. Dalteparin sodium (Fragmin) acts in the body to
A.
B.
C.
D.
E.

11. Amrinone (Inocor) is a drug that produces
A.
B.
C.
D.
E.

12. Which of the following is true of finasteride (Propecia, Proscar)?
I. useful in treating BPH
II. used to treat some types of alopecia
III. a corticosteroid
A.
B.
C.
D.
E.

13. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline is
A.
B.
C.
D.
E.

14. Which of the following is a COMT inhibitor?
A.
B.
C.
D.
E.

15. Hypoparathyroidism is a disorder that would most logically be treated with
A.
B.
C.
D.
E.

16. Which of the following agents is (are) indicated for the treatment of chronic inflammatory bowel disease?
A.
B.
C.
D.
E.

17. A uricosuric drug is one that
A.
B.
C.
D.
E.

18. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

19. Which one of the following antimicrobial agents would be MOST useful in the treatment of an infection caused by beta-Iactamase-producing staphylococci?
A.
B.
C.
D.
E.

20. Lactulose is used to treat
I. constipation
II. portal-systemic encephalopathy
III. renal tubular necrosis
A.
B.
C.
D.
E.

21. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

22. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

23. Which of the following is true of pilocarpine (Isopto Carpine, Pilostat)?
I. similar pharmacologic action to dorzolamide (Trusopt)
II. direct-acting mydriatic
III. ingredient in Ocusert ocular therapeutic system
A.
B.
C.
D.
E.

24. Which of the following is (are) true of fentanyl?
I. available as a transdermal system
II. used as a local anesthetic
III. may be used as a cough suppressant
A.
B.
C.
D.
E.

25. Finasteride (Proscar, Propecia) can best be described as a (an)
A.
B.
C.
D.
E.

26. Which of the following is (are) true of iso-tretinoin (Accutane)?
A.
B.
C.
D.
E.

27. Stavudine (Zerit) is an antiviral agent employed in the treatment of
A.
B.
C.
D.
E.

28. Which of the following beta-adrenergic blocking agents also exhibit alpha1-adrenergic blocking action?
I. timolol (Blocadren)
II. sotalol (Betapace)
III. labetalol (Normodyne, Trandate)
A.
B.
C.
D.
E.

29. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

30. Haloperidol (Haldol) differs from chlorpromazine (Thorazine) in that haloperidol
A.
B.
C.
D.
E.

31. Patients receiving amiodarone (Cordarone) should be monitored for the development of
A.
B.
C.
D.
E.

32. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

33. Endorphins are
A.
B.
C.
D.
E.

34. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

35. Which of the following is (are) true of pentamidine isethionate (Pentam, NebuPent, Pentacarinat)?
I. may be administered by inhalation
II. may be administered parenterally
III. used to treat RSV infections
A.
B.
C.
D.
E.

36. Prednisone is an agent that is employed in the treatment of
I. fungal infections
II. Crohn's disease
III. rheumatic disorders
A.
B.
C.
D.
E.

37. Which of the following agents decreases the production of hydrochloric acid in the stomach?
I. olsalazine
II. calcium carbonate
III. lansoprazole
A.
B.
C.
D.
E.

38. Which of the following statements is (are) true of potassium?
I. It is a divalent cation.
II. It facilitates the utilization of glucose by cells.
III. It is the principal intracellular ion.
A.
B.
C.
D.
E.

39. Which of the following drugs is (are) classified as a selective serotonin reuptake inhibitor (SSRI)?
I. citalopram (Celexa)
II. sertraline (Zoloft)
III. venlafaxine (Effexor)
A.
B.
C.
D.
E.

40. Gingival hyperplasia, hirsutism, and ataxia are adverse effects associated with the use of
A.
B.
C.
D.
E.

41. Thiazide diuretics decrease the excretion of
A.
B.
C.
D.
E.

42. In the treatment of cardiac arrhythmias, sotalol (Betapace) is most similar in action to
A.
B.
C.
D.
E.

43. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

44. The primary site of action of triamterene (Dyrenium) and spironolactone (Aldactone) is the
A.
B.
C.
D.
E.

45. After oral administration, the greatest amount of iron absorption occurs in the
A.
B.
C.
D.
E.

46. Which of the following agents is (are) classified as a leukotriene receptor antagonist?
I. ipratropium bromide
II. zileuton
III. montelukast sodium
A.
B.
C.
D.
E.

47. Which of the following drugs is (are) sulfonamides?
A.
B.
C.
D.
E.

48. Which one of the following barbiturates is likely to be the shortest acting?
A.
B.
C.
D.
E.

49. Metoclopramide (Reglan) is most similar in action to which of the following drugs?
A.
B.
C.
D.
E.

50. Which of the following drugs is (are) H1-histamine receptor antagonists?
I. diphenhydramine
II. hydroxyzine
III. famotidine
A.
B.
C.
D.
E.

51. Phosphate binding is likely to occur when which of the following antacids are administered?
I. aluminum hydroxide
II. sodium bicarbonate
III. calcium carbonate
A.
B.
C.
D.
E.

52. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.

53. Which of the following agents have cortical stimulant action?
I. buspirone
II. pemoline
III. methamphetamine
A.
B.
C.
D.
E.

54. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

55. Which of the following is (are) classified as a broad-spectrum antifungal agent?
I. fluorouracil
II. mebendazole
III. miconazole
A.
B.
C.
D.
E.

56. Which of the following drugs is (are) classified as protease inhibitors?
I. cidofovir
II. acyclovir
III. nelfinavir
A.
B.
C.
D.
E.

57. Trifluridine is useful in the treatment of epithelial keratitis caused by
A.
B.
C.
D.
E.

58. Ramipril HCl (Altace) can best be classified as a (an)
A.
B.
C.
D.
E.

59. Which of the following agents is (are) indicated for use in the treatment of emesis?
I. dronabinol (Marinol)
II. granisetron (Kytril)
III. nalbumetone (Relafen)
A.
B.
C.
D.
E.

60. Which of the following is (are) true of sim-vastatin (Zocor)?
I. HMG-CoA reductase inhibitor
II. pregnancy category X
III. antiviral
A.
B.
C.
D.
E.