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1. Which of the following is (are) employed as an antifungal agent?
I. cycloserine
II. mafenide
III. terbinafine
A.
B.
C.
D.
E.

2. The most serious potential consequence of ingestion of a liquid hydrocarbon such as kerosene or gasoline is
A.
B.
C.
D.
E.

3. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

4. A drug that decreases the formation of uric acid is
A.
B.
C.
D.
E.

5. Which of the following beta-adrenergic blocking agents is beta1-selective?
I. betaxolol (Betoptic)
II. metipranolol HCl (OptiPranolol)
III. timolol (Timoptic)
A.
B.
C.
D.
E.

6. Which of the following agents have cortical stimulant action?
I. buspirone
II. pemoline
III. methamphetamine
A.
B.
C.
D.
E.

7. Sulfonamides exert their antimicrobial effect by competitively inhibiting the action of
A.
B.
C.
D.
E.

8. Didofenac sodium (Voltaren) is most similar in action to
A.
B.
C.
D.
E.

9. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

10. Which of the following drugs may be used in the treatment of diabetes insipidus?
A.
B.
C.
D.
E.

11. Which one of the following antihistamines would be LEAST likely to cause sedation?
A.
B.
C.
D.
E.

12. Metoclopramide (Reglan) is most similar in action to which of the following drugs?
A.
B.
C.
D.
E.

13. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

14. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

15. Which of the following drugs may interfere with ethanol metabolism?
I. metronidazole (Flagyl)
II. chlorpropamide (Diabinese)
III. disulfiram (Antabuse)
A.
B.
C.
D.
E.

16. Prednisone is an agent that is employed in the treatment of
I. fungal infections
II. Crohn's disease
III. rheumatic disorders
A.
B.
C.
D.
E.

17. Which of the following hormones is released from the posterior pituitary gland?
I. growth hormone
II. follicle-stimulating hormone (FSH)
III. oxytocin
A.
B.
C.
D.
E.

18. Which of the following is (are) true of dobut amine (Dobutrex)?
I. antidepressant
II. only administered parenterally
III. beta! agonist
A.
B.
C.
D.
E.

19. The thiazide derivative diazoxide (Hyperstat)
A.
B.
C.
D.
E.

20. Which one of the following agents can be administered with ampicillin and other penicillins to achieve higher blood levels of the penicillin?
A.
B.
C.
D.
E.

21. Which of the following agents is (are) indicated for the treatment of convulsive disorders
I. clonidine
II. tiagabine
III. topiramate
A.
B.
C.
D.
E.

22. Although classified as antibiotics, dactinomycin (Cosmegen) and plicamycin (Mithracin) are used in cancer chemotherapy because they have a (an)
A.
B.
C.
D.
E.

23. Ramipril HCl (Altace) can best be classified as a (an)
A.
B.
C.
D.
E.

24. Lactase enzyme is available for the treatment of
A.
B.
C.
D.
E.

25. Which of the following statements is (are) true of potassium?
I. It is a divalent cation.
II. It facilitates the utilization of glucose by cells.
III. It is the principal intracellular ion.
A.
B.
C.
D.
E.

26. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

27. Which of the following agents is NOT likely to reduce blood sugar in a patient with type II diabetes mellitus?
I. glucagon
II. pioglitazone
III. repaglinide
A.
B.
C.
D.
E.

28. Stavudine (Zerit) is an antiviral agent employed in the treatment of
A.
B.
C.
D.
E.

29. Which of the following cancer chemotherapeutic agents is (are) classified as an antimetabolite?
I. mercaptopurine (Purinethol)
II. fluorouracil (Adrucil)
III. cytarabine (Cytosar-U)
A.
B.
C.
D.
E.

30. Reduced clotting ability of the blood is associated with the administration of
I. clopidogrel (Plavix)
II. abciximab (ReoPro)
III. filgrastim (Neupogen)
A.
B.
C.
D.
E.

31. Cromolyn sodium (Intal, Nasalcrom, Opticrom) is a drug that is
A.
B.
C.
D.
E.

32. The primary function of simethicone in antacid products is to act as a (an)
A.
B.
C.
D.
E.

33. Which one of the following drugs is employed in treating acute attacks of gout?
A.
B.
C.
D.
E.

34. Cyclophosphamide (Cytoxan) is an example of a (an)
A.
B.
C.
D.
E.

35. Which one of the following statements is TRUE of beclomethasone dipropionate (Beclovent, Vanceril) aerosol?
A.
B.
C.
D.
E.

36. Finasteride (Proscar, Propecia) can best be described as a (an)
A.
B.
C.
D.
E.

37. Which of the following is (are) true of ticlopidine HCl (Ticlid)?
I. inhibits platelet aggregation
II. dissolves blood clots
III. only administered parenterally
A.
B.
C.
D.
E.

38. Which of the following statements is (are) true of "crack"?
I. It is a free-base form of cocaine.
II. Its use results in eNS depression.
III. It is generally injected intravenously.
A.
B.
C.
D.
E.

39. Which of the following drugs is (are) H1-histamine receptor antagonists?
I. diphenhydramine
II. hydroxyzine
III. famotidine
A.
B.
C.
D.
E.

40. Which of the following is a COMT inhibitor?
A.
B.
C.
D.
E.

41. Which of the following statements is (are) TRUE of buprenorphine (Buprenex)?
I. It is a narcotic agonist-antagonist drug.
II. It is only administered parenterally.
III. It is a phenothiazine derivative.
A.
B.
C.
D.
E.

42. Which one of the following is an example of a pure narcotic antagonist?
A.
B.
C.
D.
E.

43. The renal excretion of amphetamines can be diminished by alkalinization of the urine. Which of the following would tend to diminish the excretion rate of amphetamine sulfate?
I. methenamine mandelate
II. acetazolamide
III. sodium bicarbonate
A.
B.
C.
D.
E.

44. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

45. Which of the following is (are) considered to be prokinetic agents?
I. lansoprazole
II. diphenoxylate
III. metoclopramide
A.
B.
C.
D.
E.

46. Which of the following agents decreases the production of hydrochloric acid in the stomach?
I. olsalazine
II. calcium carbonate
III. lansoprazole
A.
B.
C.
D.
E.

47. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

48. Which of the following agents is (are) used for the treatment of migraine headaches?
I. rizatriptan benzoate
II. methysergide maleate
III. succinylcholine chloride
A.
B.
C.
D.
E.

49. The dose of liothyronine sodium that is approximately equivalent to 100 ).!g of levothyroxine sodium (Synthroid) USP is
A.
B.
C.
D.
E.

50. Which one of the following antibiotics is a third-generation cephalosporin?
A.
B.
C.
D.
E.

51. The agent most similar in pharmacological action to miglitol (Glyset) is
A.
B.
C.
D.
E.

52. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

53. Danazol (Danocrine) can best be classified as a (an)
A.
B.
C.
D.
E.

54. Patients receiving amiodarone (Cordarone) should be monitored for the development of
A.
B.
C.
D.
E.

55. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

56. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

57. Which of the following can be classified as an osmotic laxative?
A.
B.
C.
D.
E.

58. Didanosine (Videx) can best be described as a (an)
A.
B.
C.
D.
E.

59. Agent(s) indicated for the treatment of depression include(s)
I. bupropion (Wellbutrin)
II. venlafaxine (Effexor)
III. citalopram (Celexa)
A.
B.
C.
D.
E.

60. An agent that would be most likely to cause drug-induced bronchospasm is
A.
B.
C.
D.
E.