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1. Repaglinide (Prandin) is believed to work by
A.
B.
C.
D.
E.

2. Lactulose is used to treat
I. constipation
II. portal-systemic encephalopathy
III. renal tubular necrosis
A.
B.
C.
D.
E.

3. Three hundred milligrams of phenoxymethyl penicillin is equivalent to approximately how many units of penicillin activity?
A.
B.
C.
D.
E.

4. Which of the following agents decreases the production of hydrochloric acid in the stomach?
I. olsalazine
II. calcium carbonate
III. lansoprazole
A.
B.
C.
D.
E.

5. Latanoprost (Xalatan) is a drug used in the treatment of glaucoma. Which one of the following best describes its pharmacological action?
A.
B.
C.
D.
E.

6. Of the following glucocorticoids, which one has the greatest anti-inflammatory potency when administered systemically?
A.
B.
C.
D.
E.

7. Acyclovir (Zovirax) is indicated for the treatment of
A.
B.
C.
D.
E.

8. Zafirlukast (Accolate) is a drug that can best be classified as a (an)
A.
B.
C.
D.
E.

9. The primary function of simethicone in antacid products is to act as a (an)
A.
B.
C.
D.
E.

10. Liotrix is a thyroid preparation that contains
I. desiccated thyroid
II. levothyroxine sodium
III. liothyronine sodium
A.
B.
C.
D.
E.

11. A drug indicated for the treatment of both diarrhea and constipation is
A.
B.
C.
D.
E.

12. Which of the following agents is (are) an anabolic steroid?
I. oxandrolone
II. stanozolol
III. fluorometholone
A.
B.
C.
D.
E.

13. Gastric intrinsic factor is a glycoprotein that is required for the gastrointestinal absorption of
A.
B.
C.
D.
E.

14. Which of the following statements is (are) true of fentanyl?
I. It is a narcotic agonist analgesic.
II. It is available as a transmucosal system.
III. It is available as a transdermal system.
A.
B.
C.
D.
E.

15. Sulfones such as dapsone are employed commonly in the treatment of
A.
B.
C.
D.
E.

16. Stavudine (Zerit) is an antiviral agent employed in the treatment of
A.
B.
C.
D.
E.

17. Which of the following morphine derivatives is most likely to cause dependence?
A.
B.
C.
D.
E.

18. Which of the following are employed clinically as intranasal steroids?
I. budesonide (Rhinocort)
II. fluticasone propionate (Flonase)
III. nedocromil (Tilade)
A.
B.
C.
D.
E.

19. Amrinone (Inocor) is a drug that produces
A.
B.
C.
D.
E.

20. Which of the following is a gold compound?
I. aurothioglucose (Solganal)
II. goserelin acetate (Zoladex)
III. ergonovine
A.
B.
C.
D.
E.

21. Which of the following is true of naratriptan (Amerge)?
I. It is a 5-HT1-receptor antagonist.
II. It may be administered orally or by inhalation.
III. It must be used regularly to prevent migraine headaches.
A.
B.
C.
D.
E.

22. A drug that decreases the formation of uric acid is
A.
B.
C.
D.
E.

23. Which of the following drugs is (are) sulfonamides?
A.
B.
C.
D.
E.

24. Which of the following statements is (are) true of regular insulin?
I. It is a suspension.
II. It may be administered either SC or IV.
III. It is longer acting than lispro insulin.
A.
B.
C.
D.
E.

25. Which of the following antianxiety agents causes the least sedation?
A.
B.
C.
D.
E.

26. Which of the following drugs is (are) classified as a selective serotonin reuptake inhibitor (SSRI)?
I. citalopram (Celexa)
II. sertraline (Zoloft)
III. venlafaxine (Effexor)
A.
B.
C.
D.
E.

27. Which of the following agents is NOT likely to reduce blood sugar in a patient with type II diabetes mellitus?
I. glucagon
II. pioglitazone
III. repaglinide
A.
B.
C.
D.
E.

28. Which of the following statements is (are) true of metronidazole (Flagyl)?
I. It is indicated for the treatment of migraine headaches.
II. It is used to treat superficial fungal infections.
III. It has antiprotozoal activity.
A.
B.
C.
D.
E.

29. Which one of the following is an effect of atropine on the human body?
A.
B.
C.
D.
E.

30. Which of the following is a COMT inhibitor?
A.
B.
C.
D.
E.

31. Lactase enzyme is available for the treatment of
A.
B.
C.
D.
E.

32. Which of the following is true of finasteride (Propecia, Proscar)?
I. useful in treating BPH
II. used to treat some types of alopecia
III. a corticosteroid
A.
B.
C.
D.
E.

33. An agent that would be most likely to cause drug-induced bronchospasm is
A.
B.
C.
D.
E.

34. Carbon monoxide exerts its toxic effects primarilyby
A.
B.
C.
D.
E.

35. Which one of the following barbiturates is likely to be the shortest acting?
A.
B.
C.
D.
E.

36. The "first-dose" effect is characterized by marked hypotension and syncope on taking the first few doses of medication. This effect is seen with the use of
1. doxazosin (Cardura)
II. enalapril (Vasotec)
III. sotalol (Betapace)
A.
B.
C.
D.
E.

37. Most antipsychotic drugs can be said to have which of the following actions?
A.
B.
C.
D.
E.

38. Methadone (Dolophine) is a (an)
I. analgesic drug
II. controlled substance
III. narcotic antagonist
A.
B.
C.
D.
E.

39. Nicardipine (Cardene) is indicated for the treatment of
I. angina pectoris
II. hypertension
III. ventricular tachycardia
A.
B.
C.
D.
E.

40. Which of the following agents is (are) used for the treatment of migraine headaches?
I. rizatriptan benzoate
II. methysergide maleate
III. succinylcholine chloride
A.
B.
C.
D.
E.

41. As an antiarrhythmic drug, tocainide is most similar in action to which one of the following agents?
A.
B.
C.
D.
E.

42. Which of the following is (are) true of pentamidine isethionate (Pentam, NebuPent, Pentacarinat)?
I. may be administered by inhalation
II. may be administered parenterally
III. used to treat RSV infections
A.
B.
C.
D.
E.

43. Sumatriptan (Imitrex) is most commonly employed in the treatment of
A.
B.
C.
D.
E.

44. Advantages of acetaminophen (Tylenol, APAP) over aspirin include all of the following EXCEPT
A.
B.
C.
D.
E.

45. Diflunisal (Dolobid) is most likely to be prescribed for the treatment of
A.
B.
C.
D.
E.

46. Which of the following can be classified as an osmotic laxative?
A.
B.
C.
D.
E.

47. Isotretinoin (Accutane) is a drug employed in the treatment of severe recalcitrant cystic acne. Which one of the following is NOT an adverse effect associated with its use?
A.
B.
C.
D.
E.

48. Prolonged activity (8 to 10 hours) is an advantage in the use of which of the following topical decongestants?
I. phenylephrine
II. oxymetazoline
III. xylometazoline
A.
B.
C.
D.
E.

49. Prolonged use of organic nitrates (eg, nitroglycerin) is likely to result in the development of
A.
B.
C.
D.
E.

50. Deferoxamine mesylate (Desferal) is considered to be a specific antidote for the treatment of poisoning caused by
A.
B.
C.
D.
E.

51. The thiazide derivative diazoxide (Hyperstat)
A.
B.
C.
D.
E.

52. Which of the following drugs is (are) H1-histamine receptor antagonists?
I. diphenhydramine
II. hydroxyzine
III. famotidine
A.
B.
C.
D.
E.

53. Which of the following statements is (are) true of potassium?
I. It is a divalent cation.
II. It facilitates the utilization of glucose by cells.
III. It is the principal intracellular ion.
A.
B.
C.
D.
E.

54. Which one of the following antimicrobial agents would be MOST useful in the treatment of an infection caused by beta-Iactamase-producing staphylococci?
A.
B.
C.
D.
E.

55. Which one of the following beta-adrenergic blocking agents has the greatest lipid solubility?
A.
B.
C.
D.
E.

56. A uricosuric drug is one that
A.
B.
C.
D.
E.

57. Aspirin is believed to inhibit clotting by its action on which of the following endogenous substances?
A.
B.
C.
D.
E.

58. Which of the following agents is (are) classified pharmacologically as carbonic anhydrase inhibitors?
I. fluvastatin
II. nitroprusside
III. acetazolamide
A.
B.
C.
D.
E.

59. A common adverse effect associated with the chronic use of magnesium antacids is
A.
B.
C.
D.
E.

60. Which one of the following agents is most similar in action to cloxacillin?
A.
B.
C.
D.
E.